Author

Isobelle Wall

King's College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:benchmarking· 2 Approach:experimental assay· 2 Assay:spatial transcriptomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Anita E. GrigoriadisiD· 4 shared Jelmar QuistiD· 3 shared Elena Alberts· 2 shared Gregory E VergheseiD· 2 shared Mengyuan LiiD· 2 shared Alex Jordan· 1 shared An Qi XuiD· 1 shared Ananya BhallaiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersCancer Biology

Anita E. GrigoriadisORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Mural β3-integrin signposts Stroma6, a gene signature predicting early relapse in low-risk and chemoresistant breast cancer

Alex Jordan, Vimala Anthonydhason, Katie Baird, Eleni Maniati, Janet Louise Jones, Isobelle Wall, Anita E. Grigoriadis, Jun Wang, Tarek Abdelfatah, Kairbaan Hodivala‐Dilke

The paper identifies a 6-gene stromal signature, Stroma6, that predicts early relapse in low-risk and chemoresistant breast cancer patients, independent of Oncotype DX results.

bioRxiv · Sep 16, 2026 · PreprintCancer Biology

Extrafollicular plasma cells disable dendritic cell-T-cell priming in tumor-draining lymph nodes

Elena Alberts, Victoire Boulat, Miu Shing Hung, An Qi Xu, Jelmar Quist, Mengyuan Li, Fangfang Liu, Isobelle Wall, Gregory E Verghese, Carin Andrea Brundin, Ananya Bhalla, Mats Jönsson, Carlos A. Castellanos, James Rosekilly, Cheryl Gillett, , Dinis Pedro Calado

The paper identifies extrafollicular plasma cells as an antibody-independent checkpoint that inhibits dendritic cell-T-cell priming in tumor-draining lymph nodes, leading to poor prognosis and immune-checkpoint resistance.

bioRxiv · Apr 22, 2026 · PreprintImmunology

SMART: A Spatio-Molecular Atlas of Response Trajectories in Triple-Negative Breast Cancer

Isobelle Wall, Anthony Baptista, Jelmar Quist, Holly Rafique, Mengyuan Li, Lucy Ryan, Gregory E Verghese, Stefania Marcotti, Thomas A. Phillips, Claudia Owczarek, Signe Clausen, Trine Tramm, Graham Booker, Anca Mera, Jasmine Timbres, , Anita E. Grigoriadis

The paper introduces SMART, a spatio-molecular atlas of TNBC response trajectories, revealing distinct epithelial archetypes and tumor-immune microenvironments associated with treatment response and prognosis.

bioRxiv · Aug 27, 2025 · PreprintCancer Biology

NoButter: An R package for reducing transcript dis-persion in CosMx Spatial Molecular Imaging Data

Beibhinn O'Hora, Roman Laddach, Rosamond A. Nuamah, Elena Alberts, Isobelle Wall, Joseph Bell, David A Johnston, Sonya James, Jeanette Norman, Mark G. Jones, Ciro Chiappini, Anita E. Grigoriadis, Jelmar Quist

NoButter reduces transcript dispersion in CosMx Spatial Molecular Imaging data by excluding high-dispersion Z-slices, improving data quality.

bioRxiv · Nov 25, 2024 · PreprintBioinformatics