Author

Karthik Pullela

The University of QueenslandORCID 0000-0002-9901-567XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:E. coli· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Emily C. A. GoodalliD· 2 shared Ian R. HendersoniD· 2 shared Jessica L. RookeiD· 2 shared Adam F. CunninghamiD· 1 shared Antoine DelhayeiD· 1 shared Brian M. FordeiD· 1 shared Bryan W. DayiD· 1 shared Budi PermanaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

Emily C. A. GoodallORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Vi-TIS: a transposon insertion sequencing framework for quantitative discrimination of viable and non viable mutants

Jessica L. Rooke, Karthik Pullela, Emily C. A. Goodall, Adam F. Cunningham, Daniela Vollmer, Waldemar Vollmer, Ian R. Henderson

Vi-TIS improves TIS accuracy by excluding dead cells using PMA, enhancing essential gene identification and revealing new antibiotic susceptibility patterns in E. coli.

bioRxiv · May 29, 2026 · PreprintMicrobiology

Genome scale identification of new genes using saturated reporter transposon mutagenesis

Emily C. A. Goodall, Freya J Hodges, Weine Kok, Budi Permana, Thom Cuddihy, Zihao Yang, Nicole Kahler, Kenneth Shires, Karthik Pullela, Von Vergel L. Torres, Jessica L. Rooke, Antoine Delhaye, Jean‐François Collet, Jack Alfred Bryant, Brian M. Forde, , Ian R. Henderson

The paper identifies new protein-coding sequences in E. coli using transposon mutagenesis and translation reporters, revealing previously unannotated genes.

Nucleic Acids Research · Jul 30, 2025Peer-reviewedMicrobiology

Shared molecular regulation of quiescence in neural and glioma stem cells reveals therapeutic vulnerabilities.

Chandra Choudhury, Matthew Singleton, Stephanie Brauer, Dana Friess, Jessica A. Hart, Niclas Skarne, Karthik Pullela, Likai Mao, Bryan W. Day, Lachlan Harris

This study identifies shared molecular mechanisms regulating quiescence in neural and glioma stem cells and suggests TGF-β inhibition as a potential therapeutic strategy.

bioRxiv · Jan 22, 2025 · PreprintCancer Biology