Early Neutrophil Sensing Shapes the Innate Response to Preneoplastic Mammary Cells
Antoine Debiesse, Manuela Pereira-Abrantes, Lyvia Moudombi, Aurélien Voissière, Leïla Lefèvre, Pacôme Lecot, Céline Rodriguez, Marine Malfroy, Iryna Moskalevska, Hélène Vanacker, Margaux Hubert, Albert Ndour, Roxane M. Pommier, Cassandra Assaf, Pierre Duplouye, , Marie‐Cécile Michallet
This study identifies neutrophils as the earliest immune cells involved in surveilling preneoplastic breast cancer cells through UPR activation and immunogenic signaling.
bioRxiv · Jan 17, 2025 · PreprintImmunology