Marie‐Cécile Michallet

The paper examines the spatial organization of dendritic cell subsets in NSCLC patients treated with anti-PD1 and finds that cDC1-driven patterns correlate with prolonged ICB response.

This study identifies CRY-NLRP3 complexes as a circadian checkpoint that modulates inflammasome activation and drug response, showing time-of-day effects on inflammation and drug efficacy.

IntegrAlign integrates multiimmunofluorescence panels through image alignment, achieving sub-cellular precision and improving spatial analysis of tumor microenvironments.

The paper shows reduced TLR9 expression in breast cancer cells and links it to decreased proliferation and activation of senescence-related factors.

This study identifies neutrophils as the earliest immune cells involved in surveilling preneoplastic breast cancer cells through UPR activation and immunogenic signaling.