Author

Daniel Candinas

University of BernORCID 0000-0002-9924-1749Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:Bayesian inference· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Deborah StrokaiD· 3 shared Guido BeldiiD· 3 shared Adrian KeoghiD· 2 shared Daniel Sánchez‐TaltavulliD· 2 shared Joël ZindeliD· 2 shared Nicolas MéliniD· 2 shared Noëlle DommanniD· 2 shared Bas G. J. SurewaardiD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersDevelopmental Biology

Deborah StrokaORCID

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3 papers

Recent·Most cited

Single cell chronoatlas of regenerating mouse livers reveals early Kupffer cell proliferation

Daniel Sánchez‐Taltavull, Tess Melinda Brodie, Joël Zindel, Noëlle Dommann, Bas G. J. Surewaard, Adrian Keogh, Nicolas Mélin, Isabel Büchi, Riccardo Tombolini, Paul Kubes, Daniel Candinas, Guido Beldi, Deborah Stroka

This study creates a single-cell time atlas of mouse liver regeneration after partial hepatectomy, revealing Kupffer cells as the first proliferating cell type.

bioRxiv · Jun 9, 2021 · PreprintDevelopmental Biology

Bayesian Correlation is a robust similarity measure for single cell RNA-seq data

Daniel Sánchez‐Taltavull, Theodore J. Perkins, Noëlle Dommann, Nicolas Mélin, Adrian Keogh, Daniel Candinas, Deborah Stroka, Guido Beldi

The paper introduces Bayesian correlation as a robust similarity measure for scRNA-seq data, showing it outperforms Pearson correlation in reproducibility and biological relevance.

NAR Genomics and Bioinformatics · Jan 24, 2020Peer-reviewedBioinformatics

Connexin-43 dependent ATP release mediates macrophage activation during peritonitis

Michel Dosch, Joël Zindel, Fadi Jebbawi, Nicolas Melin, Daniel Sanchez-Taltavull, Deborah Stroka, Daniel Candinas, Guido Beldi

This study shows that Connexin-43-mediated ATP release from macrophages via TLR-2 and -4 agonists promotes sepsis severity, and inhibiting this pathway improves survival in peritonitis.

bioRxiv · Sep 23, 2018 · PreprintImmunology