Daniel Sánchez‐Taltavull

Stress-induced vtRNA1-1 modulates redox homeostasis and ferroptosis susceptibility in hepatocellular carcinoma cells

This study identifies vtRNA1-1 as a short ncRNA that modulates ferroptosis susceptibility in HCC cells by regulating redox homeostasis through a reciprocal loop with NF-κB.

Released Bacterial ATP Shapes Local and Systemic Inflammation during Abdominal Sepsis

This study investigates how bacteria release ATP during sepsis and shows that bacterial ATP suppresses local immune responses and exacerbates systemic inflammation through outer membrane vesicles.

Single cell chronoatlas of regenerating mouse livers reveals early Kupffer cell proliferation

This study creates a single-cell time atlas of mouse liver regeneration after partial hepatectomy, revealing Kupffer cells as the first proliferating cell type.

Absolute quantification of transcription factors reveals principles of gene regulation in erythropoiesis

The paper quantifies transcription factor abundances during human erythropoiesis and reveals gene regulatory principles and imbalances in coactivator-corepressor ratios.

Bayesian Correlation is a robust similarity measure for single cell RNA-seq data

The paper introduces Bayesian correlation as a robust similarity measure for scRNA-seq data, showing it outperforms Pearson correlation in reproducibility and biological relevance.

Uncovering Robust Patterns of MicroRNA Co-Expression across Cancers using Bayesian Relevance Networks

This paper introduces Bayesian Relevance Networks to improve co-expression analysis of miRNA data by accounting for uncertainty in high-throughput sequencing, showing better reproducibility and lower false discovery rates.