Guido Beldi

This study investigates how bacteria release ATP during sepsis and shows that bacterial ATP suppresses local immune responses and exacerbates systemic inflammation through outer membrane vesicles.

This study creates a single-cell time atlas of mouse liver regeneration after partial hepatectomy, revealing Kupffer cells as the first proliferating cell type.

The paper introduces Bayesian correlation as a robust similarity measure for scRNA-seq data, showing it outperforms Pearson correlation in reproducibility and biological relevance.

This study shows that Connexin-43-mediated ATP release from macrophages via TLR-2 and -4 agonists promotes sepsis severity, and inhibiting this pathway improves survival in peritonitis.