Activation of lateral hypothalamic group III mGluRs suppresses drug-seeking following abstinence and cocaine-associated increases in excitatory drive to orexin/hypocretin cells
Jiann Wei Yeoh, Morgan H. James, Cameron D. Adams, Jaideep Singh Bains, Takeshi Sakurai, Gary Aston‐Jones, Brett Anthony Graham, Christopher V. Dayas
This study shows that activating group III mGluRs in the lateral hypothalamus reduces orexin cell activity and suppresses cocaine-seeking behavior during abstinence.
Neuropharmacology · Sep 22, 2018Peer-reviewedNeuroscience