Takeshi Sakurai

The paper identifies dynamical signatures and a mathematical principle underlying the transition from normothermia to hypothermia in mammals.

This study shows hypothermia, not hypometabolism, suppresses reproductive activity in mice by reducing arcuate kisspeptin neuron activity during energy-saving conditions.

This study shows psilocybin selectively affects GABAergic interneurons in the mouse medial frontal cortex, reducing somatostatin-expressing and increasing parvalbumin-expressing neuron activity.

The paper shows that inducing a hibernation-like brain state in AD mice slows amyloid plaque accumulation and reduces neuroinflammation without targeting specific pathways.

This study uses a mouse model of artificial hibernation to show that specific synaptic engram structures are preserved despite widespread spine and synapse elimination, suggesting their role in long-term memory retention.

This study shows that artificially induced hypothermia during pregnancy in mice causes fetal growth impairment and pregnancy loss, highlighting the importance of maternal body temperature in fetal development.

This paper identifies RPa-vGluT3 neurons as critical regulators of thermogenesis by coordinating sympathetic and somatic motor outputs to increase body temperature.

This study identifies dual acetylcholine-dopamine dynamics in the ventral shell of the nucleus accumbens that drive sequential transitions of male sexual behaviors in mice.

The paper introduces T-scope V4, a miniaturized microscope that enables simultaneous neuronal activity imaging and optogenetic manipulation in freely moving mice by preventing biological crosstalk.

CaliAli improves neuronal tracking in calcium imaging by aligning sessions before extracting features, enhancing detection of weak signals and enabling long-term dynamics analysis.

This study shows that activating group III mGluRs in the lateral hypothalamus reduces orexin cell activity and suppresses cocaine-seeking behavior during abstinence.