Author

Takanobu A. Katoh

RIKEN Center for Biosystems Dynamics ResearchORCID 0000-0002-9966-6798Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Hiroshi HamadaiD· 3 shared Eriko Kajikawa· 2 shared Hiromi NishimuraiD· 2 shared Katsura MinegishiiD· 2 shared Xiaorei SaiiD· 2 shared Yasushi OkadaiD· 2 shared Yayoi Ikawa· 2 shared Atsuko Hikikoshi IwaneiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersDevelopmental Biology

Hiroshi HamadaORCID

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3 papers

Recent·Most cited

BMP4 regulates asymmetric Pkd2 distribution in mouse nodal immotile cilia and ciliary mechanosensing required for left-right determination

Takanobu A. Katoh, Tim Lange, Yoshiro Nakajima, Kenta Yashiro, Yasushi Okada, Hiroshi Hamada

Developmental Dynamics · Jul 10, 2024Peer-reviewedDevelopmental Biology

Immotile cilia of the mouse node sense a fluid flow-induced mechanical force for left-right symmetry breaking

Takanobu A. Katoh, Toshihiro Omori, Katsutoshi Mizuno, Xiaorei Sai, Katsura Minegishi, Yayoi Ikawa, Hiromi Nishimura, Takeshi Itabashi, Eriko Kajikawa, Sylvain Hiver, Atsuko Hikikoshi Iwane, Takuji Ishikawa, Yasushi Okada, Takayuki Nishizaka, Hiroshi Hamada

The paper shows that immotile cilia in mouse node cells detect mechanical forces from leftward fluid flow, leading to asymmetric molecular responses that break left-right symmetry.

Science · Jan 5, 2023Peer-reviewedDevelopmental Biology

Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires Bicc1-Ccr4 RNA degradation complex

Katsura Minegishi, Benjamin Rothé, Kaoru R. Komatsu, Hiroki Ono, Yayoi Ikawa, Hiromi Nishimura, Takanobu A. Katoh, Eriko Kajikawa, Xiaorei Sai, Emi Miyashita, Katsuyoshi Takaoka, Kana Bando, Hiroshi Kiyonari, Tadashi S. Yamamoto, Hirohide Saito, , Hiroshi Hamada

The paper investigates how fluid flow induces asymmetric Dand5 mRNA decay in the mouse embryo through the Bicc1-Ccr4 RNA degradation complex.

Nature Communications · Jul 1, 2021Peer-reviewedDevelopmental Biology