Yasushi Okada

This paper introduces a method to enable continuous single-molecule tracking beyond photobleaching limits by designing reversible probe exchange kinetics.

This study identifies circumferential actomyosin bundles as drivers of endothelial cell deformations that regulate vessel diameter and prevent vascular malformations.

This study identifies amino acid substitutions in KIF5A from giraffes and pythons that enhance axonal transport speed, revealing convergent evolutionary adaptations for long-distance transport.

This paper introduces UpDPC, a label-free microscopy technique that enhances resolution and sensitivity for subcellular organelle visualization on standard microscopes.

This study uses computational modeling and molecular dynamics simulations to elucidate the proton-transfer coupled rotation mechanism of MotAB in bacterial flagellar motors.

The paper develops a universal platform for single fluorescent protein-based FLIM biosensors capable of detecting multiple analytes with a dynamic range of 0.5 to 1.0 ns.

The paper shows that immotile cilia in mouse node cells detect mechanical forces from leftward fluid flow, leading to asymmetric molecular responses that break left-right symmetry.