Author

Yayoi Ikawa

RIKEN Center for Biosystems Dynamics Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

Hiroshi HamadaiD· 3 shared Eriko Kajikawa· 2 shared Hiromi NishimuraiD· 2 shared Katsura MinegishiiD· 2 shared Takanobu A. KatohiD· 2 shared Xiaorei SaiiD· 2 shared Atsuko Hikikoshi IwaneiD· 1 shared Benjamin RothéiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

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10 top collaborators · 42 mutual co-author links

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3 shared papersDevelopmental Biology

Hiroshi HamadaORCID

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3 papers

Recent·Most cited

Localization and function of key axonemal microtubule inner proteins and dynein docking complex members reveal extensive diversity among vertebrate motile cilia

Hao Lu, Wang Kyaw Twan, Yayoi Ikawa, Vani Prem Khare, Ishita Mukherjee, Kai Xin Chua, Saikat Chakrabarti, Hiroshi Hamada, Sudipto Roy

The paper investigates the localization and function of axonemal microtubule inner proteins and dynein docking complex members in vertebrate motile cilia, revealing structural and functional differences between (9+2) and (9+0) cilia.

bioRxiv · Feb 14, 2024 · PreprintDevelopmental Biology

Immotile cilia of the mouse node sense a fluid flow-induced mechanical force for left-right symmetry breaking

Takanobu A. Katoh, Toshihiro Omori, Katsutoshi Mizuno, Xiaorei Sai, Katsura Minegishi, Yayoi Ikawa, Hiromi Nishimura, Takeshi Itabashi, Eriko Kajikawa, Sylvain Hiver, Atsuko Hikikoshi Iwane, Takuji Ishikawa, Yasushi Okada, Takayuki Nishizaka, Hiroshi Hamada

The paper shows that immotile cilia in mouse node cells detect mechanical forces from leftward fluid flow, leading to asymmetric molecular responses that break left-right symmetry.

Science · Jan 5, 2023Peer-reviewedDevelopmental Biology

Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires Bicc1-Ccr4 RNA degradation complex

Katsura Minegishi, Benjamin Rothé, Kaoru R. Komatsu, Hiroki Ono, Yayoi Ikawa, Hiromi Nishimura, Takanobu A. Katoh, Eriko Kajikawa, Xiaorei Sai, Emi Miyashita, Katsuyoshi Takaoka, Kana Bando, Hiroshi Kiyonari, Tadashi S. Yamamoto, Hirohide Saito, , Hiroshi Hamada

The paper investigates how fluid flow induces asymmetric Dand5 mRNA decay in the mouse embryo through the Bicc1-Ccr4 RNA degradation complex.

Nature Communications · Jul 1, 2021Peer-reviewedDevelopmental Biology