Author

Deniz Uğurlu-Çimen

Koç UniversityORCID 0000-0002-9970-4870Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Developmental Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

Abigail LohiD· 1 shared Afaf Alsubhi· 1 shared Aida Maria Bertoli‐AvellaiD· 1 shared Ajay Sriram MathuruiD· 1 shared Arda ÇetinkayaiD· 1 shared Ayse Gurel· 1 shared Beril TalimiD· 1 shared Bertrand BoissoniD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetic & Genomic Medicine

Abigail LohORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

AF10 (MLLT10) prevents somatic cell reprogramming through regulation of H3K79 methylation

Deniz Uğurlu-Çimen, Deniz Odluyurt, Kenan Sevinç, Nazlı Ezgi Özkan, Burcu Özçimen, Deniz Demirtaş, Eray Enüstün, Can Aztekin, Martin Philpott, Udo C. T. Oppermann, Nurhan Özlü, Tamer T. Önder

This study identifies AF10 as a barrier to somatic cell reprogramming by regulating H3K79 methylation, showing that its suppression enhances reprogramming efficiency.

Epigenetics & Chromatin · Jul 2, 2021Peer-reviewedDevelopmental Biology

Loss of C2orf69 defines a fatal auto-inflammatory mitochondriopathy in Humans and Zebrafish

Hui Hui Wong, Sze Hwee Seet, Michael Maier, Ayse Gurel, Ricardo Moreno Traspas, Cheryl Q. E. Lee, Shan Zhang, Beril Talim, Abigail Loh, Crystal Y. Chia, Tze Shin Teoh, Danielle Sng, Jarred W. Rensvold, Şule Ünal, Evgenia Shishkova, , Bruno Reversade

The paper identifies C2orf69 deficiency as a cause of a fatal auto-inflammatory syndrome in humans and zebrafish, affecting mitochondrial function and immune/cNS development.

The American Journal of Human Genetics · May 25, 2021Peer-reviewedGenetic & Genomic Medicine