Alexandra E. Wehmeyer

The paper identifies two regulatory modules that control the sequential transition between early and late gastrulation modes in mouse gastruloids.

This study shows that Nodal and Wnt signalling act antagonistically during mammalian gastrulation, with Nodal promoting anterior structures and Wnt driving posterior development.

The paper investigates the distinct gene-regulatory functions of Eomes and Brachyury in mouse embryos and stem cells, showing Eomes restricts Brachyury activity to ensure proper lineage specification.

This paper introduces chimeric 3D-gastruloids as a tool to study mammalian peri-gastrulation development by combining genetically distinct cells to investigate gene function and phenotypes.