Xingyu Liu

This study identifies IGF2 as a therapeutic target in PRC2-deficient MPNSTs by linking PRC2 loss to chromatin remodeling and activation of the IGF2-IGF2BP axis.

The paper develops GlycanDIA, a DIA-based workflow for glycan identification and quantification, showing improved sensitivity and the ability to detect low-abundant modified glycans.

The paper introduces GAP-MS to study glycan-dependent PPIs and shows it identifies PPI variations under different glycosylation conditions.

The paper introduces SCAP, a method combining affinity purification, live cell imaging, and cross-linking mass spectrometry to build integrative structural models of protein complexes.