Yixin Xu

The paper reports the structure of the mammalian ciliary transition zone microtubule doublet using cryo-electron tomography, revealing unique proteins and their roles in microtubule stabilization and transport regulation.

The paper introduces MiCSPARC, a cryo-EM pipeline for microtubule structure determination, achieving high-resolution reconstructions of decorated and undecorated microtubules.

This paper reports cryo-EM structures of NEDD1 bound to the human γ-TuRC with and without CDK5RAP2, revealing how NEDD1 anchors the complex and orients its microtubule-binding domains.

This study determines the structure of the gamma-tubulin ring complex (gamma-TuRC) activated by CDK5RAP2 and shows how it promotes microtubule nucleation by closing the gamma-tubulin ring.