Daniel X. Zhang

This study presents the cryo-EM structure of the C. elegans γ-TuRC, revealing how it templates 11-protofilament microtubules through a divergent 4-spoked assembly.

The paper introduces MiCSPARC, a cryo-EM pipeline for microtubule structure determination, achieving high-resolution reconstructions of decorated and undecorated microtubules.

This study uses cryo-EM to determine the near-atomic structure of the archaeal virus HFTV1, revealing insights into its assembly, infection mechanisms, and host-virus interactions.

This paper reports cryo-EM structures of NEDD1 bound to the human γ-TuRC with and without CDK5RAP2, revealing how NEDD1 anchors the complex and orients its microtubule-binding domains.