Author
University of PennsylvaniaORCID 0009-0006-5281-2504Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Qu Deng, Erick Mitchell-Velasquez, Sharan Venkatesh…·Irfan Ahmed Asangani
This study identifies NNMT as a tumor suppressor in prostate cancer that regulates SAM availability, mTORC1 signaling, and chromatin methylation, revealing a therapeutic strategy using dietary methionine restriction and mTORC1 inhibition.
Amy C. Gladstein, Carson D. Poltorack, Charles Solomon Akino Mercy…·David M. Feldser
The paper shows that H3K36M oncohistone inhibits NSD2, leading to SETD2-dependent antiviral immune response and tumor clearance in KRAS-driven lung cancer.
Christina Demetriadou, Michael Noji, Austin L. Good…·Kathryn E. Wellen
This study identifies a nuclear branched-chain amino acid catabolism pathway in pancreatic cancer that regulates histone propionylation and gene expression.
Abhijit Parolia, Sanjana Eyunni, Brijesh Kumar Verma…·Irfan Ahmed Asangani
This study identifies NSD2 as a critical component of the AR neo-enhanceosome in prostate cancer, showing its role in AR enhancer circuitry and tumor progression.