Author

Tarah J. Yared

Boston CollegeORCID 0000-0003-0064-9582Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Organism:human· 1 Research Focus:protein design· 1 Assay:proteomics· 1

Frequent Co-Authors

Abhishek ChatterjeeiD· 2 shared Rachel L. HuangiD· 2 shared Bharathi SundareshiD· 1 shared Delilah JeweliD· 1 shared Elise D. FicarettaiD· 1 shared Lena A. Voss· 1 shared Quan Thanh PhamiD· 1 shared Rachel E. Kelemen· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersSynthetic Biology

Abhishek ChatterjeeORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintNov 27, 2024

Optimized directed evolution of E. coli leucyl-tRNA synthetase adds many noncanonical amino acids into the eukaryotic genetic code including ornithine and Nepsilon-acetyl-methyllysine

Elise D. Ficaretta, Tarah J. Yared, Subrata Bhattacharjee…·Abhishek Chatterjee

This study optimizes a yeast-based directed evolution platform to expand the substrate scope of EcLeuRS, enabling incorporation of noncanonical amino acids like ornithine into mammalian cells.

DOI 10.1101/2024.11.27.625662

E. coliproteomics

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Synthetic BiologyACS Synthetic BiologyPeer-reviewedJun 21, 2024

Directed evolution of a bacterial leucyl tRNA in mammalian cells for enhanced noncanonical amino acid mutagenesis

Rachel L. Huang, Delilah Jewel, Rachel E. Kelemen…·Abhishek Chatterjee

This paper improves the efficiency of noncanonical amino acid incorporation in mammalian cells by evolving tRNAEcLeu through directed evolution in mammalian cells.

13 citations

humanCRISPR screen

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