Jean‐Marie Garnier

The study identifies specific TAF8 regions critical for TFIID lobe B assembly and TAF2 interactions, showing their necessity for mouse embryonic stem cell survival.

The paper shows that mammalian nuclear transcription complexes assemble co-translationally, with dimerization domains dictating the assembly pathway.

This study develops an in vitro protocol to recapitulate early paraxial mesoderm development in mouse ES cells, showing efficient differentiation into muscle precursor cells and functional muscle fibers.

The paper identifies a novel protein complex, WHHERE, that regulates retinoic acid signaling and embryonic symmetry by controlling histone modifications and RNA Polymerase II recruitment.