Hongchang Li

This study identifies cortactin's role in suppressing mTOR-dependent senescence in CTCs, leading to metastatic dormancy, and proposes a therapeutic strategy combining cortactin depletion and senolytics.

The paper uses single-cell RNA sequencing to compare immune characteristics in HBV-positive and HBV-negative HCC, finding HBV alters immune cell composition and T cell function.

This paper develops a machine learning model to identify iPS progenitor cells using microscopic image analysis, achieving over 52% precision in detecting these rare cells during early reprogramming.