Igor Siwanowicz

The paper shows macrophages remove protein aggregates from other cells via trogocytosis, driven by lysosomal stress and tmCSF1 signaling.

This study identifies and characterizes motor neurons controlling antennal movement in Drosophila, revealing their functional roles in sensory positioning.

The paper studies how dragonfly wings deform and how mechanosensors encode this information, showing that wing structure passively constrains deformation patterns to simplify sensing.

The paper introduces WHOLISTIC, a method to image cellular activity across all organs of a vertebrate, revealing body-wide circuits and responses to stimuli.

This study identifies a proprioceptive sensor in Drosophila legs that detects movement limits and mediates sensorimotor reflexes through specific neural connections.

This paper develops a detailed biomechanical model of fruit flies for simulating locomotion using reinforcement learning.

The paper introduces a new collection of over 800 split-GAL4 and split-LexA drivers for studying associative learning in Drosophila, covering 300 cell types and enabling functional analysis of neural circuits.

The paper investigates target-selective descending neurons in dragonflies during prey interception flight, finding they stabilize prey on the eye rather than directly controlling steering.

The paper uses machine learning to model how insect wing hinge muscles control wing motion and aerodynamic forces.

1328 descending and 733 motor neurons of the male Drosophila nerve cord connectome were curated; direct links between them are infrequent, and intrinsic-neuron communities route control per motor system.

The paper identifies 196 cell types in the Drosophila ventral nerve cord using split-GAL4 and links them to a connectomic dataset for circuit analysis.

The paper shows that the preferred directions of Drosophila DS neurons are shaped by the compound eye's structure, linking peripheral anatomy to neural function and behavior.

The paper investigates biomechanical and molecular mechanisms underlying proprioceptor diversity in Drosophila legs, identifying a biomechanical basis for joint angle selectivity and a goniotopic map of joint angle.

The paper identifies a novel family of secreted proteins, BICYCLE, in aphids that are associated with plant gall development through differential gene expression.

This study maps the neuroanatomy and sensor distribution in dragonfly wings to understand how mechanosensors detect aeroelastic deformations during flight.

The paper sequences and annotates the genome of Parhyale hawaiensis, identifying key genes for development, immunity, and lignocellulose digestion, providing a resource for comparative studies.