Miriam Abele

This study identifies PP2A phosphatase as a potential dephosphorylating enzyme for TRAPPII subunit TRS120 in Arabidopsis, linking kinase-phosphatase balance to membrane trafficking.

The paper identifies sequence adaptations in the intracellular domain of SymRK that enable infection thread progression in root nodule primordia by interacting with SINA E3 ubiquitin ligases.

This study uses proteogenomics to show that transposable elements in Blumeria hordei generate novel transcripts and proteins.

The paper identifies SAGA CORE subunits as essential for KAT2A stability, showing that their disruption leads to proteasomal degradation of KAT2A and reduced H3K9 acetylation.

The paper identifies a novel gene cluster in Bifidobacterium pseudolongum that enables resistant starch utilization, linking CAZyme profiles to niche adaptation in infant and adult microbiomes.

The paper identifies inhibitor-induced kinase destabilization as a common phenomenon and reveals that it occurs through endogenous proteolytic mechanisms rather than classical ubiquitination.

The paper develops a method to identify and validate kinase-substrate relationships using phosphoproteomics data and applies it to estimate kinase activity in cancer biopsies.

The paper uses chemical proteomics to analyze KRAS inhibitor effects on signaling networks in cancer cells, revealing cell-specific responses and phosphorylation changes.

The paper engineers Parageobacillus thermoglucosidasius to use methanol via the RuMP cycle for growth, achieving 17% biomass from methanol without heterologous enzyme expression.

The paper shows that CemR regulates metabolic pathways in Campylobacteria to adapt to oxygen availability, impacting ATP production and growth.