Yifei Zhou

The paper investigates whether glycogen phosphorylase (GP) can be an insecticidal target in Plutella xylostella by evaluating the effects of GP inhibitors and showing that metabolic compensation via gluconeogenesis prevents insecticidal activity.

This study shows that AMPK regulates NPP-16/NUP50 to enhance lipid catabolism and extend C. elegans lifespan, independent of its nuclear transport function.

This study identifies H3K27ac as a key transcriptional switch that promotes longevity by enhancing lipid catabolism and antioxidant defenses under hormetic nutrient stress in C. elegans.

This study shows phenformin extends lifespan in C. elegans more consistently than metformin, which is affected by environmental factors like agar batch.

This study identifies ether lipid biosynthesis as a key pathway mediating the longevity benefits of biguanides like metformin in C. elegans.

The paper shows that TORC2 deficiency in C. elegans slows development through the Hh/Patched signaling pathway and the transcription factor pqm-1.

This study shows that riboflavin depletion in C. elegans extends lifespan and improves metabolic health through multiple pathways.