Author

Zhonghe Sun

Leidos Biomedical Research Inc. (United States)ORCID 0000-0003-0098-3871Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:long-read sequencing· 1 Organism:mouse· 1

Frequent Co-Authors

Xiaolin WuiD· 2 shared Anjali Nandal· 1 shared Arati RaziuddiniD· 1 shared Austin T.K. HokeiD· 1 shared Bao Quoc TraniD· 1 shared Castle Raley· 1 shared Charalampos S. FloudasiD· 1 shared Christine N. MilleriD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Xiaolin WuORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 19, 2025

In vivo CRISPR screening identifies NF1/RASA1/TP53 co-mutations and downstream MEK signaling as a common key mechanism of sinonasal tumorigenesis

Kenny Vu, Sreenivasulu Gunti, Ramya Viswanathan…·Nyall R. London

This study identifies NF1/RASA1/TP53 co-mutations and MEK signaling as key drivers of sinonasal tumorigenesis through in vivo CRISPR screening and drug response testing.

DOI 10.1101/2025.05.19.654661

mousegenetic perturbation / CRISPR

𝕏 PostBluesky

GeneticsbioRxivPreprintJan 9, 2018

PacBio library preparation using blunt-end adapter ligation produces significant artefactual fusion DNA sequences

Paul Griffith, Castle Raley, David Sun…·Xiaolin Wu

The paper identifies artefactual fusion DNA sequences produced by blunt-end adapter ligation in PacBio library preparation and recommends an alternative A/T overhang method to reduce them.

8 citations

long-read sequencingexperimental assay

𝕏 PostBluesky