BiochemistryNature Chemical BiologyPeer-reviewed
Paenilamicins from the honey bee pathogen Paenibacillus larvae are context-specific translocation inhibitors of protein synthesis
Timm O. Koller, Max J. Berger, Martino Morici…·Daniel N. Wilson
This study determines the structure of paenilamicin PamB2 bound to stalled ribosomes, revealing its mechanism as a context-specific translocation inhibitor of protein synthesis.