Author

Daniel Bertrand

HiQScreen (Switzerland)ORCID 0000-0003-2057-7133Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

Chris UlensiD· 2 shared Marijke BramsiD· 2 shared Anant GharpureiD· 1 shared Andrew QuigleyiD· 1 shared Casey I. GallagheriD· 1 shared Cédric GovaertsiD· 1 shared Els PardoniD· 1 shared Genevieve L. EvansiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Chris UlensORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedMar 13, 2026

Structure of a pH-sensitive pentameric ligand-gated ion channel from the Sarcoptes scabies mite

Jessica Matos Kleiz-Ferreira, Marijke Brams, Peter J. Harrison…·Chris Ulens

This study determines the structure of a pH-sensitive ion channel from the scabies mite and shows how ivermectin modulates its activity through pH-dependent conformational changes.

2 citations

cryo-EMexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintSep 17, 2019

A functionally conserved mechanism of modulation via a vestibule site in pentameric ligand-gated ion channels

Marijke Brams, Cédric Govaerts, Kumiko Kambara…·Chris Ulens

The paper identifies a conserved vestibule binding site in pLGICs and shows nanobodies can act as allosteric modulators, expanding drug design possibilities.

DOI 10.1101/770719

protein structureexperimental assay

𝕏 PostBluesky