NeurosciencebioRxivPreprint
Harnessing cGAS-STING signaling to counteract the genotoxic-immune nexus in tauopathy
Himanshi Singh, Sazzad Khan, Jianfeng Xiao…·Mohammad Moshahid Khan
This study identifies a cGAS-STING signaling loop driving neuroinflammation and tau pathology in tauopathies, showing its disruption can alleviate disease symptoms.