Author

Rachel A. Ridgway

Cancer Research UK Scotland InstituteORCID 0000-0003-0198-8244Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Owen James SansomiD· 3 shared Andrew D. CampbelliD· 2 shared Simon John LeedhamiD· 2 shared Aideen E. RyaniD· 1 shared Aik Seng NgiD· 1 shared Amelia LigezaiD· 1 shared Andrea LeesiD· 1 shared Andrew Young· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

Owen James SansomORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologyCommunications BiologyPeer-reviewedMay 26, 2026

Viral mimicry redirects immunosuppressed colorectal tumour landscapes towards a proinflammatory and CMS1-like regenerative state

Shania M. Corry, Svetlana S. Sakhnevych, Noha Ehssan Mohamed…·Philip D. Dunne

This study shows that poly(I:C) treatment in CMS4 colorectal tumors induces a pro-inflammatory, CMS1-like regenerative state and identifies biomarkers for predicting therapeutic response.

DOI 10.1038/s42003-026-10295-9

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologyNature CommunicationsPeer-reviewedJan 8, 2026

SOX2 empowers a rapid tumorigenic programme from the tumour resistant population in the skin

Patricia P. Centeno, Christopher Chester, Georgios Kanellos…·Owen James Sansom

This study identifies SOX2 as a key driver of rapid tumorigenesis from a previously resistant skin cell population in mice, with implications for human cutaneous squamous cell carcinoma.

5 citationstop 2%

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologyNature CommunicationsPeer-reviewedJun 4, 2025

GREMLIN1 disrupts intestinal epithelial-mesenchymal crosstalk to induce a wnt-dependent ectopic stem cell niche via stromal remodelling

Eoghan J. Mulholland, Hayley L. Belnoue-Davis, Gabriel N. Valbuena…·Simon John Leedham

Pathological epithelial GREM1 expression induces therapeutically reversible ectopic stem cell niches through stromal remodelling.

11 citations

mousehuman

𝕏 PostBluesky