Author

Georgios Kanellos

Cancer Research UK Scotland InstituteORCID 0000-0002-2467-4523Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Owen James SansomiD· 2 shared A.P. TurnbulliD· 1 shared Adrianna DąbrowskaiD· 1 shared Allyson M. Voelker· 1 shared Amit GuptaiD· 1 shared Andrew D. CampbelliD· 1 shared Camila Pasquali· 1 shared Catriona A. FordiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Owen James SansomORCID

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2 papers

Recent·Most cited

SOX2 empowers a rapid tumorigenic programme from the tumour resistant population in the skin

Patricia P. Centeno, Christopher Chester, Georgios Kanellos, Catriona A. Ford, Patrizia Cammareri, Gareth J. Inman, Thomas J. Jamieson, Rachel A. Ridgway, Richard Marais, Andrew D. Campbell, Owen James Sansom

This study identifies SOX2 as a key driver of rapid tumorigenesis from a previously resistant skin cell population in mice, with implications for human cutaneous squamous cell carcinoma.

Nature Communications · Jan 8, 2026Peer-reviewedCancer Biology

The differential mechanisms of eIF4A1-mediated translational activation instructed by distinct RNA features

Tobias Schmidt, A.P. Turnbull, Amit Gupta, Joseph A. Waldron, Katie Pollock, June Munro, Ridvan Nepravishta, Pauline Herviou, Adrianna Dąbrowska, Kelly Hodge, Allyson M. Voelker, Leon Pang, Camila Pasquali, Georgios Kanellos, Sara R. Zanivan, , Martin Bushell

This study identifies how eIF4A1 differentially activates translation based on mRNA features, revealing distinct mechanisms for mRNA selection and inhibition by eFT226 and hippuristanol.

bioRxiv · Mar 24, 2025 · PreprintCell Biology