Viral mimicry redirects immunosuppressed colorectal tumour landscapes towards a proinflammatory and CMS1-like regenerative state
Shania M. Corry, Svetlana S. Sakhnevych, Noha Ehssan Mohamed, Sudhir B. Malla, Ryan M. Byrne, Andrew Young, Raheleh Amirkhah, Courtney Bull, Andrea Lees, Keara L. Redmond, Tamsin R.M. Lannagan, Rachel A. Ridgway, Fiona R Taggart, Natalie C. Fisher, Tim Maughan, , Philip D. Dunne
This study shows that poly(I:C) treatment in CMS4 colorectal tumors induces a pro-inflammatory, CMS1-like regenerative state and identifies biomarkers for predicting therapeutic response.
Communications Biology · May 26, 2026Peer-reviewedCancer Biology