Author

Chen Zhang

Weill Cornell MedicineORCID 0000-0003-0205-0928Unclaimed ORCID profile · follow to get notified of new preprints

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Chen Zhang7 papers · Capital Medical University

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Aatur Dilip SinghiiD· 1 shared Adam C. SoloffiD· 1 shared Aditi KulkarniiD· 1 shared Adrian Vega· 1 shared Aidan C.A. TomlinsoniD· 1 shared Alain BorczukiD· 1 shared Alyna KattiiD· 1 shared Armando P. SignoreiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

Aatur Dilip SinghiORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 16, 2026

Integrative multi-omic analysis identifies tumor-intrinsic p38 as a driver of immune exclusion in human epithelial cancers

Rebekah Dadey, Krishna Beer Singh, Rose Doerfler…·Riyue Bao

This study identifies tumor-intrinsic p38 activation as a driver of immune exclusion in epithelial cancers and suggests it as a therapeutic target to overcome immunotherapy resistance.

DOI 10.64898/2026.06.11.731716

𝕏 PostBluesky

Cancer BiologybioRxivPreprintAug 4, 2025

Genetic mechanisms of resistance to targeted KRAS inhibition

Bianca Jay Diaz, M.S. Kops, Sara Bernardo…·Lukas E. Dow

This study identifies genetic mechanisms of resistance to KRAS inhibitors by using CRISPR screens to find resistance mutations and signaling rewiring in NSCLC.

2 citations

humangenetic perturbation / CRISPR

𝕏 PostBluesky

Cancer BiologybioRxivPreprintDec 31, 2024

Acquisition of discrete immune suppressive barriers contributes to the initiation and progression of preinvasive to invasive human lung cancer.

Liron Yoffe, Bhavneet Bhinder, Sung Wook Kang…·Vivek Mittal

This study identifies immune suppressive barriers in preinvasive lung cancer progression using single-cell analyses, revealing key cellular and spatial changes that could inform therapeutic strategies.

3 citations

𝕏 PostBluesky