Carl‐Philipp Heisenberg

This paper introduces Rheo-FLUCS, a probe-free method to measure cell mechanics using light-induced flows, showing equivalence to active microrheology in different biological systems.

The paper shows keratins balance spreading forces and tissue resilience in zebrafish embryos to enable uniform tissue spreading.

This study shows that early zebrafish embryo geometry guides asymmetric cell divisions and patterns zygotic genome activation, influencing cell cycle timing and developmental robustness.

The paper shows that meroblastic cleavage in zebrafish embryos involves a two-step process with mechanical uncoupling and cadherin-mediated adhesion, distinct from canonical cytokinesis.

This study identifies and characterizes Cilin, an ancient metazoan intermediate filament protein, showing its role in cilia arrangement and tissue architecture across ctenophores and other animals.

This study shows that ectoderm tissue properties, influenced by BMP signaling, modulate lateral mesendoderm cell migration during zebrafish gastrulation.

This study shows Nodal signaling promotes embryonic axis elongation by inducing mesendoderm and suppressing BMP signaling in the dorsal mesendoderm.

This paper shows hoxb genes regulate mesendoderm cell ingression timing by controlling cell surface fluctuations during zebrafish gastrulation.

The paper shows that yolk granule fusion and microtubule aster formation drive cortical granule translocation and exocytosis in zebrafish oocytes during maturation.

The paper shows how a Nodal/TGF-β morphogen gradient coordinates pattern-preserving tissue morphogenesis in zebrafish gastrulation through motility-driven (un)jamming transitions.

The paper identifies Admp as an upstream regulator of tail bending in Ciona embryos by controlling phosphorylated myosin localization and ventral epidermal cell polarity.

The paper investigates the role of Satb2 in regulating zygotic genome activation and developmental transitions during vertebrate embryogenesis, showing distinct maternal and zygotic functions.

The paper reveals that incomplete delamination in zebrafish progenitor cells enables coordinated tissue movements by maintaining apical contacts, guiding progenitors to the differentiation site through a dragging mechanism.

The paper identifies an adhesion code in zebrafish neural progenitors that ensures robust stripe-like pattern formation during spinal cord morphogenesis.

The paper shows that a contractile acto-myosin belt drives anisotropic growth in zebrafish pectoral fins by shaping the anterior-posterior to dorso-ventral axis ratio.