Mei Zhang

The paper examines TFEB and TFE3 expression and function in brain cells, showing TFEB is restricted to glia while TFE3 is widespread, with distinct roles in mitochondrial and lysosomal biogenesis in neurons.

This study uses CRISPR to knockout RHO in rhesus macaques, resulting in RP-like phenotypes and demonstrating the feasibility of creating NHP models for retinal disease research.

This study creates a single-cell transcriptome atlas of human and macaque retinas across ages, revealing species-specific molecular features and age-related changes in cell types and disease associations.

This study uses scRNA-Seq to analyze human and mouse retinal development, identifying conserved and species-specific gene expression patterns and a novel role for ATOH7 in photoreceptor specification.

This study uses single-cell RNA-seq to analyze human fetal retinal development, revealing transcriptional programs and developmental trajectories of retinal cell types.