Author

Soetkin Leys

Ghent UniversityORCID 0000-0001-7568-4660Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Angeline Praveena Enton Raj· 1 shared Annelies Van HemelrykiD· 1 shared Annika Jeschke· 1 shared Bram De WildeiD· 1 shared Ellen SandersiD· 1 shared Fanny De VloediD· 1 shared Fien Martens· 1 shared Frank SpelemaniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Angeline Praveena Enton Raj

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1 paper

Recent·Most cited

Cancer BiologyCell Death and DiseasePeer-reviewedFeb 25, 2026

Targeting replication stress in neuroblastoma by exploiting the synergistic potential of second generation RRM2 and CHK1 inhibitors

Iris H. Nelen, Soetkin Leys, Sarah-Lee Bekaert…·Kaat Durinck

This study identifies synergistic effects of second-generation RRM2 and CHK1 inhibitors in neuroblastoma and sarcomas, showing enhanced replication stress and apoptosis.

3 citationstop 2%

humanbulk RNA-seq

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