Abigail J. Smith

The paper designs synthetic proteins by deriving sequence-to-structure rules from coiled-coil tetramers and validates them through experimental methods.

This paper designs de novo protein-protein interfaces to control biomolecular interactions in E. coli, demonstrating their ability to guide engineered protein-DNA interactions and modulate gene expression.

The paper shows that gene function, as defined by GO categories, influences expression levels in S. cerevisiae, with a predictive model based on GO associations.