Eno‐Obong Essien

This study shows that targeting DNA-LNPs to endothelial cells enhances transgene expression magnitude, duration, and specificity in target organs.

This paper identifies that lipid nanoparticle-induced inflammation arises from endosomal membrane damage and proposes strategies to mitigate it through galectin inhibition or ESCRT-recruiting lipids.

The paper shows that lung marginated neutrophils effectively uptake endothelial-targeted nanoparticles, suggesting they are part of the reticuloendothelial system.