Author

Hanyu Li

Johns Hopkins UniversityORCID 0000-0003-0342-8144Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1

Frequent Co-Authors

Kundlik GadhaveiD· 2 shared Liana S. RosenthaliD· 2 shared Mingyao YingiD· 2 shared Ramhari KumbhariD· 2 shared Shu Zhang· 2 shared Ted M. DawsoniD· 2 shared Xiaobo MaoiD· 2 shared Xiaodi ZhangiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersBiochemistry

Kundlik GadhaveORCID

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2 papers

Recent·Most cited

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedJul 14, 2026

Targeted α-Synuclein mRNA Degradation by PMO-Based RNA-Degrading Chimeras

Ning Wang, Shalakha Hegde, Zhichao Tang…·Jingxin Wang

This paper develops PMO-based RNA-degrading chimeras that target SNCA mRNA to reduce α-synuclein levels and prevent pathological aggregation in vitro and in vivo.

DOI 10.1073/pnas.2526461123

mousehuman

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NeurosciencebioRxivPreprintOct 22, 2024

α-Synuclein Strain Dynamics Predict Cognitive Transitions in Parkinson's Disease

Kundlik Gadhave, Ning Wang, Kyungdo Kim…·Xiaobo Mao

The paper identifies distinct α-synuclein strains associated with cognitive decline in Parkinson's disease and shows AI-based analysis of these strains improves clinical stratification.

3 citations

humanproteomics

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