PhysiologybioRxivPreprint
Polycystin-1 C-Terminus Regulates Protein Synthesis-Related Pathways in Cardiomyocytes
Matthew J. Fiedler, Alejandra Vásquez‐Limeta, Ernesto Reyes-Sanchez…·Francisco J Altamirano
This study shows that PC1-CT in cardiomyocytes activates PI3K-Akt-mTOR-S6K1-S6 signaling to enhance protein synthesis pathways without inducing canonical hypertrophy.