Aloke Virmani Finn

This study shows that nuclear rupture in LMNA-DCM leads to transcriptional deficiency and identifies resealing as a protective mechanism that is ultimately insufficient.

This study identifies Th9 cells and IL-9R/STAT3 signaling as drivers of atherosclerosis in inflammatory conditions like psoriasis.

This study shows that a polygenic risk score for coronary artery disease is associated with more severe atherosclerosis features in autopsy samples of sudden death cases.

This study performs a meta-analysis of scRNA-seq datasets to map human atherosclerosis cell diversity and identifies disease-relevant vascular cell states and markers.

The paper uses single-cell ATAC-seq to analyze coronary artery cells from CAD patients, identifying regulatory mechanisms and risk variants associated with disease.

This study examines the association between pathogenic or likely pathogenic genetic variants in cardiomyopathy and arrhythmia genes and unexplained sudden cardiac death in adults with no gross pathological findings.