Gaelle E Auguste

This study identifies METTL7A as a mechanosensitive methyltransferase that regulates internal m7G methylation in endothelial cells, protecting against atherosclerosis through stabilization of anti-inflammatory transcripts.

This study integrates CAD GWAS with transcriptomic data to identify genes and networks associated with CAD and subclinical atherosclerosis.

This study shows PRDM16 maintains SMC identity and regulates atherosclerotic plaque composition by inhibiting synthetic gene programs during SMC fate switching.

This study shows that interferon-induced H3K9me3 and ATRX restrict HSV-1 reactivation by maintaining epigenetic memory during neuronal latency.

This study performs a meta-analysis of scRNA-seq datasets to map human atherosclerosis cell diversity and identifies disease-relevant vascular cell states and markers.

This study identifies FHL5 as a causal gene for vascular disease risk through eQTL colocalization and functional analyses, showing its role in vascular remodeling and calcification.

The paper uses single-cell ATAC-seq to analyze coronary artery cells from CAD patients, identifying regulatory mechanisms and risk variants associated with disease.