Author

Shuguang Wang

Shandong UniversityORCID 0000-0002-9381-1771Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:E. coli· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Peng‐Fei XiaiD· 5 shared Xian-Zheng YuaniD· 4 shared Pei-Ru CheniD· 3 shared Xin LiiD· 2 shared Ying WeiiD· 2 shared Bo GongiD· 1 shared Cheng-Cheng DingiD· 1 shared Haiyan YuiD· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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5 shared papersSynthetic Biology

Peng‐Fei XiaORCID

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5 papers

Recent·Most cited

Repurposing the evolutionary fitness of marine bacteria for water-conserving conversion of lignin-derived carbon

Ying Wei, Peiru Chen, Bo Gong, Xian-Zheng Yuan, Shuguang Wang, Peng‐Fei Xia

The paper repurposes marine bacteria to convert lignin-derived carbon into valuable chemicals using seawater, achieving carbon and water conservation.

Nature Communications · Oct 1, 2026Peer-reviewedBioengineering

Unravelling the constrained cell growth in engineered living materials

Shuang-Shuang Sun, Cheng-Cheng Ding, Haiyan Yu, Xian-Zheng Yuan, Shuguang Wang, Peng‐Fei Xia

This study investigates how spatial confinement affects cyanobacteria growth and functionality in engineered living materials, revealing impaired performance and altered physiology.

ACS Synthetic Biology · Aug 14, 2025Peer-reviewedBioengineering

Non-canonical cleavage expands prime editing in 5' direction

Peiru Chen, Xian-Zheng Yuan, Shuguang Wang, Peng‐Fei Xia

This paper expands prime editing capabilities by utilizing non-canonical cleavage to enable editing in the 5' direction of a classic nick site.

bioRxiv · May 20, 2025 · PreprintSynthetic Biology

Awakening prime editing for precision engineering of probiotic Escherichia coli Nissle 1917

Pei-Ru Chen, Ying Wei, Xin Li, Hou–Yong Yu, Shuguang Wang, Xian-Zheng Yuan, Peng‐Fei Xia

This paper develops a streamlined prime editing system for Escherichia coli Nissle 1917, achieving high editing efficiencies and reduced off-target effects for DNA deletion, insertion, and substitution.

Applied and Environmental Microbiology · Jan 31, 2025Peer-reviewedSynthetic Biology

One-for-all gene inactivation via PAM-independent base editing in bacteria

Xin Li, Ying Wei, Shuyan Wang, Shuguang Wang, Peng‐Fei Xia

This paper introduces XSTART, a PAM-independent base editing system for universal gene inactivation in bacteria, achieving near 100% efficiency but with off-target events.

Journal of Biological Chemistry · Dec 18, 2024Peer-reviewedSynthetic Biology