Author

Edward Hartley Sargent

Northwestern UniversityORCID 0000-0003-0396-6495Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:CRISPR screen· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Amy H.Y. TongiD· 1 shared Anika Gupta· 1 shared Ashty S. KarimiD· 1 shared Barbara MairiD· 1 shared Bastian VögeliiD· 1 shared Bharti SingaliD· 1 shared Cong TianiD· 1 shared David N. PhilpottiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Amy H.Y. TongORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintAug 8, 2024

A synthetic cell-free pathway for biocatalytic upgrading of one-carbon substrates

Grant M. Landwehr, Bastian Vögeli, Cong Tian…·Michael C. Jewett

This study presents a cell-free biocatalytic system for converting one-carbon substrates into acetyl-CoA using a synthetic pathway called ReForm.

5 citations

experimental assay

𝕏 PostBluesky

GenomicsbioRxivPreprintApr 19, 2019

Scalable, FACS-Free Genome-Wide Phenotypic Screening

Barbara Mair, Peter M. Aldridge, Randy Singh Atwal…·Shana O. Kelley

The paper presents a high-throughput CRISPR-Cas9 screening method for identifying CD47 modulators, identifying QPCTL as a key enzyme involved in its pyroglutamyl modification.

1 citation

humanCRISPR screen

𝕏 PostBluesky