Author

Joseph H.A. Vissers

The University of MelbourneORCID 0000-0003-0435-6824Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Organism:Drosophila· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Kieran F. HarveyiD· 3 shared Abdul Jabbar Saiful HilmiiD· 1 shared Alessandro GardiniiD· 1 shared Andrea NewboldiD· 1 shared Anthony T. PapenfussiD· 1 shared Ben P. Martin· 1 shared Benjamin J. BlythiD· 1 shared Colin M. HouseiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersDevelopmental Biology

Kieran F. HarveyORCID

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4 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJan 10, 2025

RNAsum: a tool for personalised genome and transcriptome interpretation for improved cancer diagnostics

Sehrish Kanwal, Jacek Marzec, Joseph H.A. Vissers…·Sean Michael Grimmond

RNAsum integrates WGS and WTS data to improve cancer diagnostics by corroborating clinically relevant variants and supporting therapeutic decisions.

DOI 10.1101/2025.01.10.24319650

humanwhole-genome sequencing

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Developmental BiologybioRxivPreprintJun 19, 2024

The JNK and Hippo pathways control epithelial integrity and prevent tumour initiation by regulating an overlapping transcriptome

Katrina A. Mitchell, Joseph H.A. Vissers, Jonathan M. Pojer…·Kieran F. Harvey

The paper identifies how JNK and Hippo pathways regulate epithelial integrity by controlling an overlapping transcriptome, preventing tumour initiation through shared gene repression.

DOI 10.1101/2024.06.19.599466

Drosophilastatistical model

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GenomicsCellPeer-reviewedMay 17, 2021

A PP2A-Integrator complex fine-tunes transcription by opposing CDK9

Stephin J. Vervoort, Sarah A. Welsh, Jennifer R. Devlin…·Ricky W. Johnstone

The paper identifies a PP2A-Integrator complex that opposes CDK9 activity to regulate transcription and shows its therapeutic synergy in leukemia.

221 citationstop 1%

humanbulk RNA-seq

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Developmental BiologyGeneticsPeer-reviewedMar 2, 2020

Pits and CtBP control tissue growth in Drosophila melanogaster with the Hippo pathway transcription repressor, Tgi.

Joseph H.A. Vissers, Lucas Dent, Colin M. House…·Kieran F. Harvey

This study identifies Pits and CtBP as Tgi-interacting proteins that cooperate in transcriptional repression of Hippo pathway target genes in Drosophila, with conservation in human orthologs.

8 citations

Drosophilaexperimental assay

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