NeuroscienceBrainPeer-reviewed
In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy
Gaia Colasante, Yichen Qiu, Luca Massimino…·Gabriele Lignani
This study uses CRISPRa to increase Kv1.1 expression in mouse hippocampal neurons, reducing seizures and cognitive deficits in a temporal lobe epilepsy model.
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