Valerie Phoebe O'Brien

This study investigates the fitness benefits and costs of the H. pylori Cag-T4SS and CagA during stomach infection, showing initial benefits and later costs due to inflammation.

This study shows that diet-induced obesity worsens pre-cancerous changes in mice infected with Helicobacter pylori, particularly in those with genetic predispositions to gastric disease.

This study shows that H. pylori-induced gastric metaplasia enables F. animalis colonization, which is associated with increased Gal-GalNAc and reduced acidity.

This study identifies Muc6-expressing isthmus progenitors as key contributors to gastric regeneration and metaplasia through myeloid-mesenchymal interactions.