Author

Cynthia X. Guo

University of TorontoORCID 0000-0003-2106-1147Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Scott D. Gray‐OweniD· 2 shared Adrienne RangeriD· 1 shared Caitlin F. HarriganiD· 1 shared Dana J. PhilpottiD· 1 shared Derek K.L. TsangiD· 1 shared Hannes Luc RöstiD· 1 shared Herbert Y. GaisanoiD· 1 shared Jacob P. FrickiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

Scott D. Gray‐OwenORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintAug 7, 2026

CagA delivery by the Helicobacter pylori Cag-Type IV Secretion System confers fitness benefits and costs during stomach infection

Jazmine A. Snow, Jacob P. Frick, Valerie Phoebe O'Brien…·Nina R. Salama

This study investigates the fitness benefits and costs of the H. pylori Cag-T4SS and CagA during stomach infection, showing initial benefits and later costs due to inflammation.

DOI 10.64898/2026.08.07.743500

mouseexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivPreprintJan 15, 2024

Bacterial ADP-heptose initiates a revival stem cell program in the intestinal epithelium

Shawn Goyal, Cynthia X. Guo, Adrienne Ranger…·Stephen E. Girardin

This study shows that bacterial ADP-heptose triggers a revival stem cell program in the intestinal epithelium by inducing Paneth cell dedifferentiation and ISC loss.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky