Synthetic BiologyCell chemical biologyPeer-reviewed
REPROGRAMMING CBX8-PRC1 FUNCTION WITH A POSITIVE ALLOSTERIC MODULATOR
Junghyun L. Suh, Daniel Bsteh, Bryce Hart…·Oliver Bell
This paper identifies UNC7040 as a potent CBX8-specific positive allosteric modulator that disrupts PRC1 function and reduces cancer cell proliferation.
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