Lorena Ruiz‐Pérez

This study models the structure of LRP1 using homology and neural network-based methods, revealing glycan-mediated dimerization and its role in stabilizing the protein's quaternary structure.

This study develops a multivalent scaffold targeting LRP1 at the BBB to reduce Aβ deposits and cognitive decline in AD model mice.

This study uses liquid-phase transmission electron microscopy to visualize Aβ aggregation dynamics and intermediate oligomers in solution.

This study investigates how syndapin-2 mediated transcytosis affects amyloid-beta clearance across the blood-brain barrier and its implications for Alzheimer's disease and aging.