Bin Guo

Targeting the IRE1α-XBP1 signaling axis impairs tumor growth and promotes myogenic differentiation in rhabdomyosarcoma

This study shows that inhibiting the IRE1α-XBP1 signaling pathway reduces tumor growth and promotes differentiation in rhabdomyosarcoma.

TAK1 is a key regulator of oncogenic signaling and differentiation blockade in rhabdomyosarcoma

This study identifies TAK1 as a key regulator of oncogenic signaling and differentiation blockade in rhabdomyosarcoma, showing its role in promoting proliferation and inhibiting myogenic differentiation.

Exome sequencing and analysis of 44,028 British South Asians enriched for high autozygosity

The paper performs whole exome sequencing on 44,028 British South Asians to identify gene-phenotype associations and knockout genes, finding novel links and implications for drug development.

Ground nesting of soft eggs by extinct birds and a new parity mode switch hypothesis for the evolution of animal reproduction

Multivalent Targeting of Blood-Brain Barrier LRP1 for Neurovascular Recovery Therapy for Alzheimer s Disease

This study develops a multivalent scaffold targeting LRP1 at the BBB to reduce Aβ deposits and cognitive decline in AD model mice.

Reorganizations of latency structure within white matter from wakefulness to sleep

The paper examines changes in white matter latency structure during wakefulness and NREM sleep using EEG-fMRI data, revealing dynamic reorganizations of signal propagation.